Endocrine Abstracts

Instruction: Most of cases reported before who were detected by FT4 or T4 newborn screening are, TSH and GH deficiency or CNS anomalies, and their hypothyroidism is mild. We report two cases of sever congenital hypothyroidism with TSH and Prolactin (PRL) deficiency, detected by TSH and FT4 screening.Case report: Case 1. K.W. boy, was born at 38 gestations, weighted 3.17 kg. Thyroid function at 5 days of age was TSH 5.6 mU...

Adrenal cortical carcinoma (ACC) is a rare malignancy, especially in children, and the annual worldwide incidence has been calculated as 0.3 cases per million children younger than 15 years old. We present a case of functioning ACC in a 7 years-old female child who manifested with virilization. She presented with low-pitched voice, excessive pubic hair growth, growth acceleration, clitoral enlargement and increased muscle strength at the age of six. Her blood pressure was norm...